0308 Impact of Customized Lighting on Sleep in Hospitalized Patients

Abstract Introduction Inpatient sleep may be disrupted for myriad reasons, including lighting exposure that is typically fixed at constant intensity and spectra. In this study we employed customized promotes circadian entrainment by exposing patients to blue-augmented during the morning blue-suppressed evening improve timing duration. Methods Two Mount Sinai hospital rooms (with 2 beds each) were outfitted with Eight Mattress sensors use a combination of movement, breathing, heart rate, temperature variables estimate wake vigilance states in 30-second epochs. One room contained between 7 am 11 pm, while other standard lighting. The current analysis includes 60 participants (30 control 30 custom room), who matched time-of-year admission date. We first analyzed probability any given epoch across each subject’s compared distributions 24-hour cycle all subjects vs conditions. additionally evaluated total nocturnal duration(11 PM – AM) 1) summating epochs on nights containing least 50% valid data 2) normalizing measured sleep/wake outputs (excluding indeterminate epochs). Results distribution was significantly different condition (p < 0.001) most apparent diversion 9 pm am. average raw duration higher (270.0 ± 23 minutes 201 min control, p = 0.037), as per hour recording (36.9 15 28.4 13 0.022). There no significant differences number or Conclusion Custom appears promote hospitalized patients, but interpretation tempered absence full validation mattress sensor against polysomnography. Future work will evaluate continuity Support (if any) McClung Foundation, R01 AG066870